The inverse problem is one of the most pressing challenges in Systems Biology today. The identification/reconstruction of gene regulatory networks from a variety of gene expression data sources is a complex task plagued, among others, by the curse of dimensionality, i.e. the striking insufficiency of observations in relation to the number of measured genes.
This talk will introduce a model-based approach to reverse-engineering gene networks from gene expression time series, using a framework of swarm intelligence techniques, namely Ant Colony and Particle Swarm Optimization. Results on artificial and real-world gene networks will also be presented and discussed. The problem domain and methods used will be introduced so that no prior subject knowledge is required.
Can ants perform inference? Gene Network Reconstruction using Swarm Intelligence

04.06.2009
Speaker : Kyriakos Kentzoglanakis
Date : 04.06.2009
Time: 14:00-15:00
Location : "Mediterranean Studies" Seminar Room, FORTH. Heraklion, Crete
Host : Ioannis (Yanni) Tollis
Date : 04.06.2009
Time: 14:00-15:00
Location : "Mediterranean Studies" Seminar Room, FORTH. Heraklion, Crete
Host : Ioannis (Yanni) Tollis
Abstract:
Bio: