Computational BioMedicine Laboratory

INTEGRATE

Category: european

Project Title: Driving Excellence in Integrative Cancer Research through Innovative Biomedical Infrastructures

Funding Organization: EC

Programme: FP7-ICT-2009.5.3, No 270253

Coordinator: PHILIPS ELECTRONICS NEDERLAND B.V., NETHERLANDS

Partners: PHILIPS ELECTRONICS NEDERLAND B.V., NETHERLANDS,CUSTODIX NV,UNIVERSIDAD POLITECNICA DE MADRID,INSTITUT JULES BORDET,FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS,BREAST INTERNATIONAL GROUP - AISBL

Duration: 01/02/2011-31/10/2014

Expiration Date: 2014

Total Budget: 5,468,898.00 €

FORTH ICS budget: 818,300.00 €

Web Site: http:// fp7-integrate.eu

Project Objective: INTEGRATE will deliver reconfigurable infrastructure components; tools for sharing and collaboration; standards-based data models; and repositories of data, models and knowledge. The INTEGRATE environment will enable: Collection, preservation, management and reuse of data collected within multi-centric clinical trials. These unique comprehensive datasets will be made available through uniform interfaces to support information sharing and collaborative knowledge generation. Multi-disciplinary collaboration, providing an environment and tools that support researchers across domains, institutions and industries to jointly contribute to research objectives, develop common methodologies and complex analyses, and efficiently make use of each other’s expertise and results. Collaborative definition and development of relevant clinical questions and more efficient validation of potential biomarker results and predictive models in clinical trials. Collaborative development, preservation and sharing of multi-scale realistic and validated predictive models of response to novel therapies and anti-cancer drugs. We will propose methodologies for model development, a modelling framework, and predictive multi-scale models in the context of breast cancer. INTEGRATE will also provide standards-based interoperability to existing research and clinical infrastructures to support efficient information reuse and integration.

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